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Background: Diabetic ketoacidosis is an acute complication of diabetes mellitus with high
occurrence of repeated admissions and 16% of deaths linked to diabetes. The duration of
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diabetes ketoacidosis recovery is dependent of different factors among which comorbidity is
the common one. Although numerous studies are conducted on this area, there are still
practical gaps in the treatment and recovery of diabetes ketoacidosis due to little attentions.
Objective: To assess time to recovery from diabetes ketoacidosis and its predictors among
type one adult diabetic patient in Ambo town hospitals, Oromia, Ethiopia, 2025.
Methods: Retrospective cohort study was done on 354 diabetic ketoacidosis patients from
April 04 – July 04, 2024. Data were collected using cheklists from selected folders and
entered to computer by EpiData 3.1 and analysed using SPSS 25. A Kaplan Meier survival
was used to estimate recovery time and log-rank test was to compare recovery time among
covariates. Bivariable and Multivariable Cox Proportional Hazards Models were fitted to
identify predictors of time to recovery. Hour is used as a time scale.
Results: The study has 89.5% response rate and the mean age of the patients was 31.62 ±
10.518 years. The median time to recovery for all observations was 52 hours, IQR (34-69).
The survival estimates of time to recovery were varied among different factors. Being in
rural residency (AHR=0.32, 95% CI: 0.14-0.75, p = 0.008), irregular follow up (AHR=0.39,
95% CI: 0.17-0.92, p = 0.032), duration of diabetes (AHR=3.24, 95% CI: 1.37-7.70),
presence of comorbidity (AHR=22.70, 95% CI: 21.72-23.62, p = 0.004), and ketone status
(AHR=0.11, 95% CI: 0.02-0.53) were predictors that significantly associated with time to
recover from diabetes ketoacidosis among type one adult diabetic patients.
Conclusion and Recommendations: The median recovery time was 52 hours, IQR (34-69).
Rural residency, follow up status, diabetes duration, comorbidity, and ketone level and were
the identified predictors of time to recovery. Concerned bodies should jointly work on the
appropriate management of diabetic ketoacidosis and diabetes educations |
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