Abstract:
Background: The second dose of measles (MCV2) was established to immunize children who
did not respond protectively to the first dose; as an added benefit, it provides a second
opportunity for measles vaccination in the second year of life. However, outbreaks continue to
occur despite the availability of safe and effective vaccinations.
Objective: This research aimed to identify determinants of defaulting from completion of the
second dose of measles vaccine among children aged 18-24 months in Ejere woreda, West Shoa,
Oromia, from February 14 to April 6, 2023
Methods: Community-based unmatched case-control study was conducted among 446 children
(110 cases and 336 controls) respondents in Ejere woreda, West shoa, Oromia, Ethiopia. Simple
random sampling technique was used to choose the study subjects. A pretested, structured
questionnaire was used to collect the data. Epi data version 3.1 software was used to enter data
and SPSS version 27 was used for the analysis. Bivariable and multivariable logistic regression
analyses were performed to find independent determinants. Variables with a p-value of < 0.25 in
the bi-variable logistic regression analysis were entered into a multivariable analysis to find
independent determinants. An adjusted odds ratio with a 95% CI and a P-value of < 0.05 were
used to identify the determinants of defaulting from MCV2.
Results: A total of 110 cases and 336 controls respondents were included in the study. Absence
of reminder given at postnatal(PNC) (AOR= 5.19; 95% CI: 2.34-7.83), Antenatal care(ANC)
contact ≤2 (AOR = 4.95; 95% CI: 2.86-9.24), long facility waiting time for the vaccine (AOR =
2.78; 95% CI: 1.19-4.38), caregiver no formal education (AOR = 6.46; 95% CI: 2.81-11.71), no
awareness on second doses of measles (AOR = 8.37; 95% CI: 4.22-15.08), and not received ≥2
doses of vitamin “A” (AOR = 4.05; 95% CI: 2.15-8.11) were found to be determinants of
defaulting from MCV2
Conclusion and Recommendations: Absence of reminder at PNC, ANC contact ≤2, long
waiting time at the health facility, caregiver education, no awareness and not receiving≥2 doses
of vitamin “A” were determinants of defaulting from MCV2. Emphasize raising awareness
creation to educate mothers, create defaulter tracing and strengthen health facilities in routine
vaccinations.
