Abstract:
Background: The second dose of measles (MCV2) was established to immunize children who
did not respond protectively to the first dose; as an added benefit, it provides a second
opportunity for measles vaccination in the second year of life. However, outbreaks continue to
occur despite the availability of safe and effective vaccinations.
Objective: This research aimed to identify determinants of defaulting from completion of the
second dose of measles among 18-24 months old children in Gindeberet district, West Shoa,
Oromia, from January 6 to March 5, 2022
Methods: Community-based unmatched case-control study was performed among 654 children
(218 cases and 436 controls). Before data collection, eligible caregivers in 11 selected subdistricts were surveyed to determine who received MCV2 in a routine national schedule from 15-
18months as (controls) and those who took the first dose only as (cases), and finally, a systematic
sampling technique was used for both. Data were collected by using a pretested and structured
questionnaire. Epi info version 7.2.2 software was used to enter data and SPSS version 26 was
used. Variables with a p-value of < 0.05 in the bi-variable logistic regression analysis were
entered into a multivariable analysis to find independent determinants. An adjusted odds ratio
with a 95% CI and a P-value of < 0.05 p-values were used to identify the determinants of
defaulting from MCV2.
Results: A total of 217 cases and 434 controls were included in the study. Absence of reminder
given at postnatal(PNC) (AOR= 4.29, 95% CI: 2.34-7.83), Antenatal care(ANC) contact ≤2
(AOR = 5.14, 95% CI: 2.86-9.24), long facility waiting time for the vaccine (AOR = 2.29, 95%
CI: 1.19-4.38), caregiver education (AOR = 5.74, 95% CI: 2.81-11.71), no awareness on second
doses of measles (AOR = 7.98, 95% CI: 4.22-15.08), not received penta3 (AOR = 4.08, 95% CI:
1.89-8.83), and not received ≥2 doses of vitamin “A” (AOR = 4.18, 95% CI: 2.15-8.11) were
found to be determinants of defaulting from MCV2
Conclusion and Recommendations: Absence of reminder at PNC, ANC contact ≤2, long
waiting time at the health facility, caregiver education, no awareness, not receiving penta3, and
not receiving≥2 doses of vitamin “A” were determinants of defaulting from MCV2. Educate
mothers, awareness creation, and strengthen and focus on timely routine vaccinations.
