Abstract:
Bacteria are frequently treated with antibiotics; however, certain strains exhibit resistance
to most of the locally available antibiotics, which leads to the generation of multidrugresistant
bacteria. These factors are significant contributors in the prevalence of infectious
diseases. Green synthesized of nanocomposite is found to be an effective antibacterial
agent because of its unique physicochemical characteristics, cost-effectiveness and ecofriendly.
In this study, the green synthesized Ni–CdO nanocomposite (NCs) was examined
for its antibacterial activity. With this regard, Ni–CdO NCs has prepared by the green
synthesis method while the characteristics of synthesized materials have been investigated
by UV–Vis, FT-IR, XRD and SEM spectroscopic techniques. Accordingly, UV–Vis
spectrum indicates energy band gap of CdO NPs and Ni-CdO NCs to be 2.19 eV and 2.03
eV, respectively. FT-IR spectrum showed that the absorption peaks are emerged
corresponding to Cd–O, Ni–O and O-H in Ni-CdO NCs and spherical shape of Ni-CdO
investigated by SEM spectrophotometer. The XRD patterns demonstrated sharp and
intensive diffraction peaks attributed to the existence of cubic CdO NPs and Ni–CdO NCs
structure revealed the decreased nanocrystalline size from 39.00 nm to 34.55 nm after Ni–
CdO NCs formation. The most effective antibacterial activity has been achieved by Ni-CdO
NCs with zone of inhibition (ZOI) of 14.5mm, 16.6mm, 14.83mm, 18.75mm and 16.25mm
against Staphylococcus aureus, Staphylococcus epidermidis, Bacillus subtilis, Escherichia
coli and Shigella, respectively. Thus, Ni-CdO NCs could be enumerated as an alternative
nanomaterial for the effective antibiotics.
