Abstract:
Background: Depression is the most prevalent mental health disorder among people living with
Human immune virus. People living with HIV/AIDS face different challenges, including HIVrelated
perceived stigma, lack of social support and also depression. Depression is highly prevalent
among HIV-positive patients, still underdiagnosed and undertreated. Identifying magnitude of
depression and its associated factors among living with Human immune virus / Acquired immune
deficiency syndrome plays a vital role to reduce its effect.
Objective: The aim of this study was to assess magnitude of depression and its associated factors
among Human immune virus / Acquired immune deficiency syndrome on Anti-retroviral therapy
follow up at public health facilities in woliso town, Oromia, Ethiopia, 2024
Methods: Institutional based cross-sectional study was conducted from February 01 to 30, 2024
among 415 Human immune virus / Acquired immune deficiency syndrome infected people in woliso
town. Simple random sampling technique was used. Data were collected through interview using
standardized questionnaire. Frequency, mean and median was used to summarize descriptive data. In
bi-variable logistic regression analysis variables with p-value less than 0.25 was considered as
candidate variables for multi-variable analysis. Adjusted Odds Ratios and 95% confidence intervals
were computed to see the strength of association and p-value of less than 0.05 was used to identify
statistically significant factors on multi-variable logistic regression.
Results: A total of 415 participated were involved in the study which makes 100% response rate.
The magnitude of depression among people living with Human immune virus was 38.1% (95% CI:
33- 42.7%). Opportunistic infection (AOR = 3.14, 95% CI 1.92-5.13), poor medication adherent to
Anti-retroviral therapy (AOR = 2.4, 95% CI 1.53-3.78), those experienced Human immune virus
related stigma (AOR = 3.09, 95% CI 1.95-4.9) and poor social support (AOR = 3.61, 95% CI 1.39-
9.39) had statistically significant association with depression among people living with Human
immune virus / Acquired immune deficiency syndrome.
Conclusions: The magnitude of depression among peoples with HIV/AIDS and on ART
follow up in Woliso town was high. Having poor social support, Human immune virus -related
perceived stigma, opportunistic infection and poor medication adherence had statistically significant
association with depressive symptom. Close follow-up for adherence for ART medication,
prevention of stigma and opportunistic infection should be strengthened
