Abstract:
Background: Human papilloma virus (HPV) is viral infection of the reproductive system that
causes cervical cancer in women. It is one of the fourth leading cause of death globally and is
second cause of sever disease and the first leading cause of death in Ethiopia. Vaccination against
HPV is effective preventive measure against cervical cancer, and the success of HPV vaccination
is determined by the readiness to accept the vaccine.
Objective: was to assess readiness to accept Human papilloma virus vaccine and its associated
factors among early adolescent girl students at elementary schools, in Ambo Rural district,
Ethiopia 2023.
Methods: A cross-sectional study was conducted among early adolescent girl students of 545
participants at elementary school in Ambo rural, central Ethiopia from October 2023 to December
2023. Study participants were selected using a simple random sampling method. Data were
collected using an interviewer administered method by online kobo collect application and
downloaded to excel, exported, and analyzed using the statistical package for the social sciences
(SPSS) version 27. Cross tab and binary logistic regression was used for data analysis. Variables
at 95%CI with a P-value of <0.25 in bi-variable logistic regression were candidates for multi
variable and those with a P-value of <0.05 in multi variable logistic regression were considered a
statistically significant. Finally, the results were narrated using text, tables, and graphs.
Result: A total, of 545 study participants were interviewed and yielded a response rate of 99.6%.
Two-thirds of responders 66.4 %( CI: 62.1%-70.3%) were ready to take HPV vaccines.
Factors significantly associated with readiness to accept vaccination:
Age: AOR; 3.69(1.85-7.35 p=.001) is positively associated with readiness to take HPV
vaccination, as age increases by one year readiness to accept HPV vaccine increase by 3.7.
Family transparency on RH: AOR .6.301; (3.935-10.093 P<0.001): Youth who live with their
family 6.3 times more likely to get supported against HPV vaccination than those who did not
Conclusion: In this study, 66.4% of participants were ready to accept HPV vaccination. This is
relatively as high as with majority of previously conducted studies. Age and Family transparency
on RH have significant association with readiness to accept HPV vaccination.
