Treatment Outcomes Of Drug Susceptible Tuberculosis Patients And Associated Factors In Public Health Facilities Of Ambo Town West Shoa Zone, Ethiopia,2024

Abstract

Introduction: Tuberculosis is a communicable disease and top cause of death from single infectious agent. More than 19000 people died in Ethiopia in 2021 because of tuberculosis. Ethiopia is among 30 high TB burden countries. The main gaps seen are; Ethiopia is among 4 countries in which tuberculosis treatment outcome is not well evaluated and no study done in Ambo town. So evaluating tuberculosis treatment outcomes and associated factors will help to achieve national plan and helps to fill this gaps. Objectives: The objective of this study was to assess the magnitude of treatment outcome of drug susceptible tuberculosis patients and its associated factors in Public Health Facilities of Ambo town West Shoa Zone, Ethiopia, 2024 Method: A retrospective study was conducted at Ambo University Referral Hospital and Ambo Health Centre on patients treated for Drug Susceptible tuberculosis from September 2016 to August 2022 by reviewing TB registration book. Data of 363 DS-TB patients who were selected by simple random technique collected with check list prepared and entered to SPSS. Subsequently Descriptive analysis; Distribution,Central tendency and Variability or dispersion and Binary Logistic regression was done to. P values less than 0.2 during Bivariable logistic regression were candidate for final model and P value less 0.05 during final model was cut point to declare level of significant Results Overall three hundred twenty four (89.3%) DS-TB patients had successful treatment outcome. From this 72(19.8%) were cured and 252 (69.4%) had completed their treatment. The remaining 39(10.7%) had unsuccessful treatment outcome with 0.8% failure, 2.5% lost follow up and 7.4% were died. Patients older than 55years (AOR=0.169, 95% CI: 0.052-0.554) and AFB negative at 6 month (AOR=6.229, 95%CI: 1.847-21.005) were predictors of treatment outcome of drug susceptible tuberculosis. Conclusion and Recommendation: The magnitude of successful treatment outcomes in this study is 89.3% (95%, 84.1-94.5) and in line with that recommended by WHO END TB STRATEGIES (≥90%).AFB negativity at 6 month and age above 55years were predictors of treatment outcome of drug susceptible tuberculosis. So older patients needs strict follow-up and further cohort study suggested