Magnitude Of Neonatal Sepsis And Its Associated Factors Among Neonates Admitted To Neonatal In Tensive Care Unit In Public Hospitals In West Shewa Zone, Ormia, Ethiopia, 2021

Abstract

Background: Neonatal sepsis is one of the principal causes of neonatal morbidity and mortality in developing countries including Ethiopia. In spite of many efforts by Ethiopia government the magnitude of neonatal sepsis remains high. Objective: To assess magnitude of neonatal sepsis and its associated factors among neonates admitted to neonatal intensive care unit of public hospitals in west Shewa zone, Oromia, Ethio pia, 2021. Methods: Institution based retrospective cross-sectional study design was conducted among ne onates admitted over a period of two years from December 1, 2019 to January30, 2021. Study participant/patient records were selected by systematic random sampling technique and the data extracted from patients chart using structured extraction checklist diploma nurses. The extracted data were entered in to EPI INFO version7 and then exported to SPSS version 25 for further analysis. Descriptive statistics, bivariate, and multivariable binary logistic regression analyses were done to identify associated factors. Then significance association was tested using 95% CI and P-values (< 0.05). Result: A total of 376 study participants involved in this study with response rate of 100%. Of the total 376 study participants, 195(51.8%; 95%CI: 46.7, 57.0%) neonates had diagnosed as ne onatal sepsis. Birth weight <2500g of neonates(AOR=3.260; 95%CI: 1.785, 6.020), meconium aspiration syndrome of neonates (AOR=4.809; 95%CI:2.591, 8.926), duration of rupture of membrane >18 hours mothers (AOR=3.186; 95%CI:1.458, 6.961), duration of labour >24 hours (AOR=2.423;95%CI:1.190, 4.934), and absence of antenatal care service during pregnancy of mothers (AOR=4.533; 95%CI:1.749, 11.747) were significantly associated with neonatal sepsis. Conclusion and Recommendation This study indicated that the magnitude of neonatal sepsis was high. Low birth weight, meconi um aspiration syndrome, prolonged rupture of membrane, prolonged duration of labour, and ab sence of antenatal care during pregnancy were found to be significantly associated with neonatal sepsis. Based on this result I recommend that encourage antenatal care service utilization, identi fication of risk during labour, follow up labour by parthograph, management of prolonged rup ture of membrane, early detection and prevention of infection should be applied to meconium aspiration syndrome, and low birth weigh